Description
Gold-Conjugates
SR offers a service of custom bioconjugation to its highly spherical 20 and 40nm citrate-stabilized gold nanoparticles. The resulting gold conjugates offer high sensitivity, precision and high stability, helping our customers to build high-performing lateral flow immunoassays. Our innovative industrial process of antibody (Biomarker) conjugation ensures a very smooth conjugation step limiting gold aggregation and allowing to reach excellent batch-to-batch reproducibility.
At SR BIOERA, we closely company our customers and their products toward high-scale manufacturing. For this perspective, we respect a 4 step-process :
Process
- Definition of the product’s technical specifications and list of Quality Control tests with expected performance criteria.
- Feasibility study including optimization of the passive adsorption conjugation conditions using e.g. antibody quantities as low as 1mg. This integrates identification of best conjugation pH, blocking agent and screening of different antibody concentrations.
- Production scale validation with three QC compliant production batches.
- Gold conjugate production and QC release following expected performance criteria.
Our custom conjugation service also includes support in the selection and sourcing of antibodies, selection of the best nanoparticle size for your specific application, and assistance in the storage buffer optimization and post-delivery technical assistance.
Our Product Features
| 40nm Custom Gold Conjugate | 20nm Custom Gold Conjugate | |
|---|---|---|
| Size | 40+/-3 nm | 20+/-3nm |
| CV On Particle Sizes | <14% | <15% |
| Sphericity | 98+% | 99+% |
| Odd Shapes Per 100 Particles | ≤1 | ≤1 |
| Optical Density | From 1 to 100 | From 1 to 100 |
| Antibody Load | From very low to saturation | |
| Suspension | Borate buffer or conjugate pad compatible | |
| Single Batch Scale | Max. 20L (OD10) | Max. 20L (OD10) |
Standard Gold Conjugate
| Product | Model Number | Od | Moq | Pack Size |
|---|---|---|---|---|
| Mouse IgG | GCMIgG | 10 | 50 ML | 50, 100, 250, 500 ML |
| Chicken IgY | GCCIgY | 10 | 50 ML | |
| Alpha HCG | GCα HCG | 10 | 50 ML | |
| Beta HCG | GCβ HCG | 10 | 50 ML | |
| Protein A | GCPA | 10 | 50 ML | |
| Protein G | GCPG | 10 | 50 ML | |
| Streptavidine | GCSL | 10 | 50 ML | |
| Biotine | GCLB | 10 | 50 ML | |
| Avidine | GCLA | 10 | 50 ML | |
| BSA | GCLB | 10 | 50 ML | |
| Thyroglobulin | GCLT | 10 | 50 ML |
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